• Comprehensive introduction to mathematical modeling, dynamic analysis, and control of cellular biomolecular processes. Emphasizes design approaches for sophisticated biomolecular networks that are robust to the environment, both in bacterial and mammalian cells. Provides a review of biology concepts and detailed description of classical and novel mechanisms to regulate gene expression. Presents how to use these mechanisms to design feedback and feedforward control architectures. Covers basic enabling technologies from synthetic biology, engineering principles for designing biological functions, modular design techniques, and host-circuit interaction. Students taking graduate version complete additional assignments.

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